Particle Toxicology

Author: Ken Donaldson
Publisher: CRC Press
ISBN: 1420003143
Size: 11.62 MB
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Traditionally, particle dosimetry has always been linked with particle toxicology,
due to the complex relationship between exposure and target dose. Unexpected
translocation of nanoparticles from the respiratory system to other organs and a
recognition that manufactured nanoparticles could affect the skin and the gut—
depending on the type of exposure—have extended the area of research.
Throughout the fifty or so years that have seen the full flowering of the scientific
discipline of ...

Case Studies In Nanotoxicology And Particle Toxicology

Author: Antonietta M Gatti
Publisher: Academic Press
ISBN: 0128012544
Size: 21.87 MB
Format: PDF
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The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians.

Stem Cell Nanoengineering

Author: H. Baharvand
Publisher: John Wiley & Sons
ISBN: 1118540727
Size: 79.32 MB
Format: PDF, Mobi
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Acute toxicological effects of copper nanoparticles in vivo. Toxicology Letters 163
: 109–120. [14] Monteiro-Riviere NA and AOInman (2006). Challenges for
assessing carbon nanomaterial toxicity to the skin. Carbon 44: 1070–1078. [15]
Bakand S, A Hayes and F Dechsakulthorn (2012). Nanoparticles: a review of
particle toxicology following inhalation exposure. Inhalation Toxicology 24: 125–
135. [16] Buzea C, II Pacheco and K Robbie (2007). Nanomaterials and
nanoparticles: ...

Mammalian Toxicology

Author: Mohamed Abou-Donia
Publisher: John Wiley & Sons
ISBN: 1118683315
Size: 59.22 MB
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From a materials science perspective, the development of new products using
engineered nanomaterials is provocative and stimulating, owing to the fact that
as movement is made in the direction of macro- or microsized particle towards
the nanoscale size– that is, decreasing the particle size range below ∼100 nm –
the physics and chemistry of particle properties are known to change or transform
. Moreover, the utilization of these changing aspects can be exploited to develop
 ...

Research Priorities For Airborne Particulate Matter

Author: National Research Council
Publisher: National Academies Press
ISBN: 9780309166287
Size: 36.28 MB
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INTRODUCTION In the preceding chapter, the committee provided its review of
progress on research topics 1-10.1 This new information will help to reduce
uncertainties in the framework for assessing the public health risks from
emissions of airborne particles and their gaseous precursors. The committee's
research portfolio is for research to investigate particle toxicity, assess human
exposures, examine biological mechanisms, identify particle sources, and
develop tools needed to ...

The Handbook Of Nanomedicine

Author: Kewal K. Jain
Publisher: Springer Science & Business Media
ISBN: 1617799831
Size: 29.16 MB
Format: PDF, ePub
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The broad scope of toxicology covers not only the adverse effects of therapeutics
but also environmental agents and poisons. Nanotoxicology covers safety issues
relevant to nanomaterials. The success of nanomaterials is due to their small size
, which enables us to get them into parts of the body where usual inorganic
materials cannot enter because of their large particle size. There is an enormous
advantage in drug delivery systems or cancer therapeutics. Current research is
trying ...

Human Toxicology Of Chemical Mixtures

Author: Harold Zeliger
Publisher: William Andrew
ISBN: 9781437734645
Size: 37.17 MB
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In urban environments, diesel exhaust particles (DEP) and fly ash residue from
power plant oil combustion are the main contributors of respirable particulates of
less than 10μm diameter (PM10). These contain mixtures of lipophiles and
hydrophiles including various metals, acid salts, aliphatic hydrocarbons, PAHs,
quinones, nitroaromatic hydrocarbons, and aldehydes [19]. Diesel combustion
particulates contain large surface areas that can adsorb large quantities of
organic ...

Nanotechnology

Author: Jo Anne Shatkin
Publisher: CRC Press
ISBN: 9781420053647
Size: 55.44 MB
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31 2.3 President's Commission framework for environmental health risk
management ............................................................................... 34 3.1 Environmental
pathways affecting water resources.......................54 4.1 Carbon nanotube
characteristics and potential adverse effects ....67 4.2 The five Ds of particle
toxicology for nanomaterials...................... 67 6.1 Proposed NANO LCRA
framework............................................... 103 7.1 Comprehensive environmental
assessment framework.

Biologic Markers In Pulmonary Toxicology

Author: Committee on Biologic Markers
Publisher: National Academies Press
ISBN: 0309597226
Size: 75.14 MB
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tation, because of interspecies differences in the distance between airborne
particles and alveolar walls. Figure 2-4 Particle deposition efficiency in human
alveolated airways. Values are means with standard deviations. Source:
Reprinted with permission from Schlesinger, 1989. From the discussion of
deposition mechanisms, it should be evident that the major particle characteristic
that influences deposition is size. A particle characteristic that can alter its size
after inhalation is ...

Issues In Global Environment Pollution And Waste Management 2011 Edition

Author:
Publisher: ScholarlyEditions
ISBN: 1464964866
Size: 34.64 MB
Format: PDF
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Particle. and. Fiber. Toxicology. Findings. from. I. Beckspeier. and. co-authors.
broaden. understanding. of. inflammation. “Ambient particulate matter (PM)-
associated metals have been shown to play an important role in cardiopulmonary
health outcomes. To study the modulation of PM-induced inflammation by
leached off metals, we investigated intracellular solubility of radiolabeled iron
oxide ((Fe2O3)-Fe-59) particles of 0.5 and 1.5 mu m geometric mean diameter,”
researchers in ...